Wiz Khalifa -- who famously raps about rolling joints "bigger than King Kong’s fingers" -- was busted for weed AGAIN last night ... the 2nd time in 10 days.

The Winston-Salem Police Department in North Carolina tells us ... the rapper was ticketed for possession of marijuana before his concert in Winston-Salem last night. We're told officers discovered 11.39 grams of pot after searching the rapper and his tour bus.

Wiz was cited and released -- and is required to appear in court at a later date.

As we previously reported, Wiz was caught with weed in Nashville on April 21 ... after cops received complaints about marijuana smoke at a local Holiday Inn.

source: tmz